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In vivo importance of heparan sulfate-binding glycoproteins for murid herpesvirus-4 infection

Many herpesviruses bind to heparan sulfate (HS). Murid herpesvirus-4 (MuHV-4) does so via its envelope glycoproteins gp70 and gH/gL. MuHV-4 gp150 further regulates an HS-independent interaction to make that HS-dependent too. Cell binding by MuHV-4 virions is consequently strongly HS-dependent. Gp70...

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Detalles Bibliográficos
Autores principales: Gillet, Laurent, May, Janet S., Stevenson, Philip G.
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885066/
https://www.ncbi.nlm.nih.gov/pubmed/19218205
http://dx.doi.org/10.1099/vir.0.005785-0

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