Generation of a Family-specific Phage Library of Llama Single Chain Antibody Fragments That Neutralize HIV-1

Recently, we described llama antibody fragments (VHH) that can neutralize human immunodeficiency virus, type 1 (HIV-1). These VHH were obtained after selective elution of phages carrying an immune library raised against gp120 of HIV-1 subtype B/C CN54 with soluble CD4. We describe here a new, family...

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Detalles Bibliográficos
Autores principales: Koh, Willie W. L., Steffensen, Soren, Gonzalez-Pajuelo, Maria, Hoorelbeke, Bart, Gorlani, Andrea, Szynol, Agnieszka, Forsman, Anna, Aasa-Chapman, Marlén M. I., de Haard, Hans, Verrips, Theo, Weiss, Robin A.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885190/
https://www.ncbi.nlm.nih.gov/pubmed/20400507
http://dx.doi.org/10.1074/jbc.M110.116699

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