Analysis of the asymmetrically expressed Ablim1 locus reveals existence of a lateral plate Nodal-independent left sided signal and an early, left-right independent role for nodal flow

BACKGROUND: Vertebrates show clear asymmetry in left-right (L-R) patterning of their organs and associated vasculature. During mammalian development a cilia driven leftwards flow of liquid leads to the left-sided expression of Nodal, which in turn activates asymmetric expression of the transcription...

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Detalles Bibliográficos
Autores principales: Stevens, Jonathan, Ermakov, Alexander, Braganca, Jose, Hilton, Helen, Underhill, Peter, Bhattacharya, Shoumo, Brown, Nigel A, Norris, Dominic P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885315/
https://www.ncbi.nlm.nih.gov/pubmed/20487527
http://dx.doi.org/10.1186/1471-213X-10-54

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