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The hemostatic profile of recombinant activated factor VII. Can low concentrations stop bleeding in off-label indications?

BACKGROUND: High concentrations of recombinant activated factor VII (rFVIIa) can stop bleeding in hemophilic patients. However the rFVIIa dose needed for stopping haemhorrage in off-label indications is unknown. Since thrombin is the main hemostatic agent, this study investigated the effect of rFVII...

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Detalles Bibliográficos
Autores principales:	Altman, Raul, Scazziota, Alejandra, de Lourdes Herrera, Maria, Gonzalez, Claudio D
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Latest therapeutic developments
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885319/ https://www.ncbi.nlm.nih.gov/pubmed/20444280 http://dx.doi.org/10.1186/1477-9560-8-8

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