The anti-aging gene KLOTHO is a novel target for epigenetic silencing in human cervical carcinoma

BACKGROUND: Klotho was originally characterized as an anti-aging gene that predisposed Klotho-deficient mice to a premature aging-like syndrome. Recently, KLOTHO was reported to function as a secreted Wnt antagonist and as a tumor suppressor. Epigenetic gene silencing of secreted Wnt antagonists is...

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Detalles Bibliográficos
Autores principales: Lee, Jaehyouk, Jeong, Dong-Jun, Kim, Jinsun, Lee, Soonduck, Park, Jin-Hwa, Chang, Boogi, Jung, Sam-Il, Yi, Lisha, Han, Youngsoo, Yang, Young, Kim, Keun Il, Lim, Jong-Seok, Yang, Inchul, Jeon, Seob, Bae, Dong Han, Kim, Chang-Jin, Lee, Myeong-Sok
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885346/
https://www.ncbi.nlm.nih.gov/pubmed/20482749
http://dx.doi.org/10.1186/1476-4598-9-109

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