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Coordination of Rho GTPase activities during cell protrusion

The GTPases Rac1, RhoA and Cdc42 act in concert to control cytoskeleton dynamics1-3. Recent biosensor studies have shown that all three GTPases are activated at the front of migrating cells4-7 and biochemical evidence suggests that they may regulate one another: Cdc42 can activate Rac18, and Rac1 an...

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Detalles Bibliográficos
Autores principales:	Machacek, Matthias, Hodgson, Louis, Welch, Christopher, Elliott, Hunter, Pertz, Olivier, Nalbant, Perihan, Abell, Amy, Johnson, Gary L., Hahn, Klaus M., Danuser, Gaudenz
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885353/ https://www.ncbi.nlm.nih.gov/pubmed/19693013 http://dx.doi.org/10.1038/nature08242

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