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Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine
BACKGROUND: Griseofulvin, an antifungal drug, has recently been shown to inhibit proliferation of various types of cancer cells and to inhibit tumor growth in athymic mice. Due to its low toxicity, griseofulvin has drawn considerable attention for its potential use in cancer chemotherapy. This work...
Autores principales: | Rathinasamy, Krishnan, Jindal, Bhavya, Asthana, Jayant, Singh, Parminder, Balaji, Petety V, Panda, Dulal |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885362/ https://www.ncbi.nlm.nih.gov/pubmed/20482847 http://dx.doi.org/10.1186/1471-2407-10-213 |
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