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Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
BACKGROUND: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the structure and chemistry of the catalytic binding site residues can be loosely defined as a substructure of the protein. Compar...
Autores principales: | Bryant, Drew H, Moll, Mark, Chen, Brian Y, Fofanov, Viacheslav Y, Kavraki, Lydia E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885373/ https://www.ncbi.nlm.nih.gov/pubmed/20459833 http://dx.doi.org/10.1186/1471-2105-11-242 |
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