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Genome-wide estimation of firing efficiencies of origins of DNA replication from time-course copy number variation data
BACKGROUND: DNA replication is a fundamental biological process during S phase of cell division. It is initiated from several hundreds of origins along whole chromosome with different firing efficiencies (or frequency of usage). Direct measurement of origin firing efficiency by techniques such as DN...
Autores principales: | Luo, Huaien, Li, Juntao, Eshaghi, Majid, Liu, Jianhua, Karuturi, R Krishna Murthy |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885374/ https://www.ncbi.nlm.nih.gov/pubmed/20462459 http://dx.doi.org/10.1186/1471-2105-11-247 |
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