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High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABERTOOTH
BACKGROUND: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become unreliable as they approach the so-called 'twilight zone' where sequence similarity gets indistinguishable fro...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885375/ https://www.ncbi.nlm.nih.gov/pubmed/20470364 http://dx.doi.org/10.1186/1471-2105-11-251 |