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Detecting microRNA activity from gene expression data

BACKGROUND: MicroRNAs (miRNAs) are non-coding RNAs that regulate gene expression by binding to the messenger RNA (mRNA) of protein coding genes. They control gene expression by either inhibiting translation or inducing mRNA degradation. A number of computational techniques have been developed to ide...

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Detalles Bibliográficos
Autores principales: Madden, Stephen F, Carpenter, Susan B, Jeffery, Ian B, Björkbacka, Harry, Fitzgerald, Katherine A, O'Neill, Luke A, Higgins, Desmond G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885376/
https://www.ncbi.nlm.nih.gov/pubmed/20482775
http://dx.doi.org/10.1186/1471-2105-11-257