Cytomegalovirus infection in pediatric rheumatic diseases: a review

Human cytomegalovirus (HCMV) is familiar to pediatric rheumatologists mainly as a cause of opportunistic disease in pharmacologically immune suppressed patients. However, HCMV also has a variety of immuno-modulatory effects, through which it may influence the course of rheumatic conditions. In this...

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Detalles Bibliográficos
Autores principales: Eisenstein, Eli M, Wolf, Dana G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885386/
https://www.ncbi.nlm.nih.gov/pubmed/20487534
http://dx.doi.org/10.1186/1546-0096-8-17
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author Eisenstein, Eli M
Wolf, Dana G
author_facet Eisenstein, Eli M
Wolf, Dana G
author_sort Eisenstein, Eli M
collection PubMed
description Human cytomegalovirus (HCMV) is familiar to pediatric rheumatologists mainly as a cause of opportunistic disease in pharmacologically immune suppressed patients. However, HCMV also has a variety of immuno-modulatory effects, through which it may influence the course of rheumatic conditions. In this article we discuss the interplay between HCMV and the immune system, and review the clinical manifestations, diagnosis, and treatment of HCMV infection in children with rheumatic disease.
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spelling pubmed-28853862010-06-15 Cytomegalovirus infection in pediatric rheumatic diseases: a review Eisenstein, Eli M Wolf, Dana G Pediatr Rheumatol Online J Review Human cytomegalovirus (HCMV) is familiar to pediatric rheumatologists mainly as a cause of opportunistic disease in pharmacologically immune suppressed patients. However, HCMV also has a variety of immuno-modulatory effects, through which it may influence the course of rheumatic conditions. In this article we discuss the interplay between HCMV and the immune system, and review the clinical manifestations, diagnosis, and treatment of HCMV infection in children with rheumatic disease. BioMed Central 2010-05-20 /pmc/articles/PMC2885386/ /pubmed/20487534 http://dx.doi.org/10.1186/1546-0096-8-17 Text en Copyright ©2010 Eisenstein and Wolf; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Eisenstein, Eli M
Wolf, Dana G
Cytomegalovirus infection in pediatric rheumatic diseases: a review
title Cytomegalovirus infection in pediatric rheumatic diseases: a review
title_full Cytomegalovirus infection in pediatric rheumatic diseases: a review
title_fullStr Cytomegalovirus infection in pediatric rheumatic diseases: a review
title_full_unstemmed Cytomegalovirus infection in pediatric rheumatic diseases: a review
title_short Cytomegalovirus infection in pediatric rheumatic diseases: a review
title_sort cytomegalovirus infection in pediatric rheumatic diseases: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885386/
https://www.ncbi.nlm.nih.gov/pubmed/20487534
http://dx.doi.org/10.1186/1546-0096-8-17
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