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Cyclic Nucleotide-Gated Channels Contribute to Thromboxane A(2)-Induced Contraction of Rat Small Mesenteric Arteries

BACKGROUND: Thromboxane A(2) (TxA(2))-induced smooth muscle contraction has been implicated in cardiovascular, renal and respiratory diseases. This contraction can be partly attributed to TxA(2)-induced Ca(2+) influx, which resulted in vascular contraction via Ca(2+)-calmodulin-MLCK pathway. This st...

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Detalles Bibliográficos
Autores principales: Leung, Yuk Ki, Du, Juan, Huang, Yu, Yao, Xiaoqiang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885410/
https://www.ncbi.nlm.nih.gov/pubmed/20559420
http://dx.doi.org/10.1371/journal.pone.0011098