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Altered Retinoic Acid Metabolism in Diabetic Mouse Kidney Identified by (18)O Isotopic Labeling and 2D Mass Spectrometry
BACKGROUND: Numerous metabolic pathways have been implicated in diabetes-induced renal injury, yet few studies have utilized unbiased systems biology approaches for mapping the interconnectivity of diabetes-dysregulated proteins that are involved. We utilized a global, quantitative, differential pro...
Autores principales: | Starkey, Jonathan M., Zhao, Yingxin, Sadygov, Rovshan G., Haidacher, Sigmund J., LeJeune, Wanda S., Dey, Nilay, Luxon, Bruce A., Kane, Maureen A., Napoli, Joseph L., Denner, Larry, Tilton, Ronald G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885420/ https://www.ncbi.nlm.nih.gov/pubmed/20559430 http://dx.doi.org/10.1371/journal.pone.0011095 |
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