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Chronic suppression of mu-opioid receptor signaling in the nucleus accumbens attenuates development of diet-induced obesity in rats

OBJECTIVE: To test the hypothesis that mu-opioid receptor signaling in the nucleus accumbens contributes to hedonic (over)eating and obesity. To investigate the effects of chronic mu-opioid antagonism in the nucleus accumbens core or shell on intake of a palatable diet, and the development of diet-i...

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Detalles Bibliográficos
Autores principales: Lenard, Natalie R., Zheng, Huiyuan, Berthoud, Hans-Rudolf
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885588/
https://www.ncbi.nlm.nih.gov/pubmed/20065959
http://dx.doi.org/10.1038/ijo.2009.297

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