Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein

Vaccinia virus (VACV) encodes many immunomodulatory proteins, including inhibitors of apoptosis and modulators of innate immune signalling. VACV protein N1 is an intracellular homodimer that contributes to virus virulence and was reported to inhibit nuclear factor (NF)-κB signalling. However, analys...

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Detalles Bibliográficos
Autores principales: Cooray, Samantha, Bahar, Mohammad W., Abrescia, Nicola G. A., McVey, Colin E., Bartlett, Nathan W., Chen, Ron A.-J., Stuart, David I., Grimes, Jonathan M., Smith, Geoffrey L.
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2007
Materias:
Jgv Direct
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885619/
https://www.ncbi.nlm.nih.gov/pubmed/17485524
http://dx.doi.org/10.1099/vir.0.82772-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885619/
https://www.ncbi.nlm.nih.gov/pubmed/17485524
http://dx.doi.org/10.1099/vir.0.82772-0

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