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Identification of the Staphylococcus aureus MSCRAMM clumping factor B (ClfB) binding site in the αC-domain of human fibrinogen

Clumping factor B (ClfB) of Staphylococcus aureus binds to cytokeratin 10 and to fibrinogen. In this study the binding site in human fibrinogen was localized to a short region within the C terminus of the Aα-chain. ClfB only bound to the Aα-chain of fibrinogen in a ligand-affinity blot and in solid-...

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Detalles Bibliográficos
Autores principales:	Walsh, Evelyn J., Miajlovic, Helen, Gorkun, Oleg V., Foster, Timothy J.
Formato:	Texto
Lenguaje:	English
Publicado:	Microbiology Society 2008
Materias:	Pathogens and Pathogenicity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885624/ https://www.ncbi.nlm.nih.gov/pubmed/18227259 http://dx.doi.org/10.1099/mic.0.2007/010868-0

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