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The nuclear export receptor XPO-1 supports primary miRNA processing in C. elegans and Drosophila

MicroRNA (miRNA) biogenesis proceeds from a primary transcript (pri-miRNA) through the pre-miRNA into the mature miRNA. Here, we identify a role of the Caenorhabditis elegans nuclear export receptor XPO-1 and the cap-binding proteins CBP-20/NCBP-2 and CBP-80/NCBP-1 in this process. The RNA-mediated...

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Detalles Bibliográficos
Autores principales:	Büssing, Ingo, Yang, Jr-Shiuan, Lai, Eric C, Großhans, Helge
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885935/ https://www.ncbi.nlm.nih.gov/pubmed/20436454 http://dx.doi.org/10.1038/emboj.2010.82

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