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The Association of Factor V Leiden and Prothrombin Gene Mutation and Placenta-Mediated Pregnancy Complications: A Systematic Review and Meta-analysis of Prospective Cohort Studies

BACKGROUND: Factor V Leiden (FVL) and prothrombin gene mutation (PGM) are common inherited thrombophilias. Retrospective studies variably suggest a link between maternal FVL/PGM and placenta-mediated pregnancy complications including pregnancy loss, small for gestational age, pre-eclampsia and place...

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Detalles Bibliográficos
Autores principales: Rodger, Marc A., Betancourt, Marisol T., Clark, Peter, Lindqvist, Pelle G., Dizon-Townson, Donna, Said, Joanne, Seligsohn, Uri, Carrier, Marc, Salomon, Ophira, Greer, Ian A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885985/
https://www.ncbi.nlm.nih.gov/pubmed/20563311
http://dx.doi.org/10.1371/journal.pmed.1000292