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Global characterization of interferon regulatory factor (IRF) genes in vertebrates: Glimpse of the diversification in evolution

BACKGROUND: Interferon regulatory factors (IRFs), which can be identified based on a unique helix-turn-helix DNA-binding domain (DBD) are a large family of transcription factors involved in host immune response, haemotopoietic differentiation and immunomodulation. Despite the identification of ten I...

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Detalles Bibliográficos
Autores principales: Huang, Bei, Qi, Zhi T, Xu, Zhen, Nie, Pin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885996/
https://www.ncbi.nlm.nih.gov/pubmed/20444275
http://dx.doi.org/10.1186/1471-2172-11-22