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Gauchos and ochos: a Wee1-Cdk tango regulating mitotic entry
The kinase Wee1 has been recognized for a quarter century as a key inhibitor of Cyclin dependent kinase 1 (Cdk1) and mitotic entry in eukaryotes. Nonetheless, Wee1 regulation is not well understood and its large amino-terminal regulatory domain (NRD) has remained largely uncharted. Evidence has accu...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886006/ https://www.ncbi.nlm.nih.gov/pubmed/20465818 http://dx.doi.org/10.1186/1747-1028-5-12 |