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Pim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity
BACKGROUND: The serine/threonine kinase PIM1 has been implicated as an oncogene in various human cancers including lymphomas, gastric, colorectal and prostate carcinomas. In mouse models, Pim1 is known to cooperate with c-Myc to promote tumorigenicity. However, there has been limited analysis of the...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886047/ https://www.ncbi.nlm.nih.gov/pubmed/20515470 http://dx.doi.org/10.1186/1471-2407-10-248 |