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Seroprevalence of Bartonella in Eastern China and analysis of risk factors

BACKGROUND: Bartonella infections are emerging in the Zhejiang Province of China. However, there has been no effort to date to explore the epidemiology of these infections in this region, nor to identify risk factors associated with exposure to Bartonella. The aim of this study was to investigate th...

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Autores principales: Sun, Jimin, Fu, Guiming, Lin, Junfen, Song, Xiuping, Lu, Liang, Liu, Qiyong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886056/
https://www.ncbi.nlm.nih.gov/pubmed/20482887
http://dx.doi.org/10.1186/1471-2334-10-121
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author Sun, Jimin
Fu, Guiming
Lin, Junfen
Song, Xiuping
Lu, Liang
Liu, Qiyong
author_facet Sun, Jimin
Fu, Guiming
Lin, Junfen
Song, Xiuping
Lu, Liang
Liu, Qiyong
author_sort Sun, Jimin
collection PubMed
description BACKGROUND: Bartonella infections are emerging in the Zhejiang Province of China. However, there has been no effort to date to explore the epidemiology of these infections in this region, nor to identify risk factors associated with exposure to Bartonella. The aim of this study was to investigate the seroprevalence of Bartonella in both patients bitten by dogs and blood donors (for control) in Eastern China, and to identify risk factors associated with exposure to Bartonella. As no previous data for this region have been published, this study will provide baseline data useful for Bartonella infection surveillance, control, and prevention. METHODS: Blood samples were collected from industrial rabies clinic attendees and blood donors living in eight areas of the Zhejiang Province of China, between December 2005 and November 2006. An indirect immunofluorescent antibody test was used to determine the presence of Bartonella in these samples. Risk factors associated with Bartonella exposure were explored using Chi-square tests and logistic regression analysis of epidemiological data relating to the study's participants. RESULTS: Bartonella antibodies were detected in 19.60% (109/556) of blood samples. Seroprevalence varied among the eight areas surveys, ranging from over 32% in Hangzhou to only 2% in Jiangshan (X(2 )= 28.22, P < 0.001). We detected a significantly higher prevalence of Bartonella antibodies in people who had been bitten by dogs than in blood donors (X(2 )= 13.86, P < 0.001). Seroprevalence of Bartonella was similar among males (18.61%, n = 317) and females (20.92%, n = 239). CONCLUSIONS: Bartonella antibodies were encountered in people living across Zhejiang Province and the seropositivity rate among those exposed to dog bites was significantly higher than that among blood donors, indicating that dog bites may be a risk factor for Bartonella infection.
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spelling pubmed-28860562010-06-16 Seroprevalence of Bartonella in Eastern China and analysis of risk factors Sun, Jimin Fu, Guiming Lin, Junfen Song, Xiuping Lu, Liang Liu, Qiyong BMC Infect Dis Research Article BACKGROUND: Bartonella infections are emerging in the Zhejiang Province of China. However, there has been no effort to date to explore the epidemiology of these infections in this region, nor to identify risk factors associated with exposure to Bartonella. The aim of this study was to investigate the seroprevalence of Bartonella in both patients bitten by dogs and blood donors (for control) in Eastern China, and to identify risk factors associated with exposure to Bartonella. As no previous data for this region have been published, this study will provide baseline data useful for Bartonella infection surveillance, control, and prevention. METHODS: Blood samples were collected from industrial rabies clinic attendees and blood donors living in eight areas of the Zhejiang Province of China, between December 2005 and November 2006. An indirect immunofluorescent antibody test was used to determine the presence of Bartonella in these samples. Risk factors associated with Bartonella exposure were explored using Chi-square tests and logistic regression analysis of epidemiological data relating to the study's participants. RESULTS: Bartonella antibodies were detected in 19.60% (109/556) of blood samples. Seroprevalence varied among the eight areas surveys, ranging from over 32% in Hangzhou to only 2% in Jiangshan (X(2 )= 28.22, P < 0.001). We detected a significantly higher prevalence of Bartonella antibodies in people who had been bitten by dogs than in blood donors (X(2 )= 13.86, P < 0.001). Seroprevalence of Bartonella was similar among males (18.61%, n = 317) and females (20.92%, n = 239). CONCLUSIONS: Bartonella antibodies were encountered in people living across Zhejiang Province and the seropositivity rate among those exposed to dog bites was significantly higher than that among blood donors, indicating that dog bites may be a risk factor for Bartonella infection. BioMed Central 2010-05-20 /pmc/articles/PMC2886056/ /pubmed/20482887 http://dx.doi.org/10.1186/1471-2334-10-121 Text en Copyright ©2010 Sun et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Sun, Jimin
Fu, Guiming
Lin, Junfen
Song, Xiuping
Lu, Liang
Liu, Qiyong
Seroprevalence of Bartonella in Eastern China and analysis of risk factors
title Seroprevalence of Bartonella in Eastern China and analysis of risk factors
title_full Seroprevalence of Bartonella in Eastern China and analysis of risk factors
title_fullStr Seroprevalence of Bartonella in Eastern China and analysis of risk factors
title_full_unstemmed Seroprevalence of Bartonella in Eastern China and analysis of risk factors
title_short Seroprevalence of Bartonella in Eastern China and analysis of risk factors
title_sort seroprevalence of bartonella in eastern china and analysis of risk factors
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886056/
https://www.ncbi.nlm.nih.gov/pubmed/20482887
http://dx.doi.org/10.1186/1471-2334-10-121
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