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Genome-wide expression links the electron transfer pathway of Shewanella oneidensis to chemotaxis
BACKGROUND: By coupling the oxidation of organic substrates to a broad range of terminal electron acceptors (such as nitrate, metals and radionuclides), Shewanella oneidensis MR-1 has the ability to produce current in microbial fuel cells (MFCs). omcA, mtrA, omcB (also known as mtrC), mtrB, and gspF...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886065/ https://www.ncbi.nlm.nih.gov/pubmed/20492688 http://dx.doi.org/10.1186/1471-2164-11-319 |
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author | Tai, Shang-Kai Wu, GuanI Yuan, Shinsheng Li, Ker-Chau |
author_facet | Tai, Shang-Kai Wu, GuanI Yuan, Shinsheng Li, Ker-Chau |
author_sort | Tai, Shang-Kai |
collection | PubMed |
description | BACKGROUND: By coupling the oxidation of organic substrates to a broad range of terminal electron acceptors (such as nitrate, metals and radionuclides), Shewanella oneidensis MR-1 has the ability to produce current in microbial fuel cells (MFCs). omcA, mtrA, omcB (also known as mtrC), mtrB, and gspF are some known genes of S. oneidensis MR-1 that participate in the process of electron transfer. How does the cell coordinate the expression of these genes? To shed light on this problem, we obtain the gene expression datasets of MR-1 that are recently public-accessible in Gene Expression Omnibus. We utilize the novel statistical method, liquid association (LA), to investigate the complex pattern of gene regulation. RESULTS: Through a web of information obtained by our data analysis, a network of transcriptional regulatory relationship between chemotaxis and electron transfer pathways is revealed, highlighting the important roles of the chemotaxis gene cheA-1, the magnesium transporter gene mgtE-1, and a triheme c-type cytochrome gene SO4572. CONCLUSION: We found previously unknown relationship between chemotaxis and electron transfer using LA system. The study has the potential of helping researchers to overcome the intrinsic metabolic limitation of the microorganisms for improving power density output of an MFC. |
format | Text |
id | pubmed-2886065 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-28860652010-06-16 Genome-wide expression links the electron transfer pathway of Shewanella oneidensis to chemotaxis Tai, Shang-Kai Wu, GuanI Yuan, Shinsheng Li, Ker-Chau BMC Genomics Methodology Article BACKGROUND: By coupling the oxidation of organic substrates to a broad range of terminal electron acceptors (such as nitrate, metals and radionuclides), Shewanella oneidensis MR-1 has the ability to produce current in microbial fuel cells (MFCs). omcA, mtrA, omcB (also known as mtrC), mtrB, and gspF are some known genes of S. oneidensis MR-1 that participate in the process of electron transfer. How does the cell coordinate the expression of these genes? To shed light on this problem, we obtain the gene expression datasets of MR-1 that are recently public-accessible in Gene Expression Omnibus. We utilize the novel statistical method, liquid association (LA), to investigate the complex pattern of gene regulation. RESULTS: Through a web of information obtained by our data analysis, a network of transcriptional regulatory relationship between chemotaxis and electron transfer pathways is revealed, highlighting the important roles of the chemotaxis gene cheA-1, the magnesium transporter gene mgtE-1, and a triheme c-type cytochrome gene SO4572. CONCLUSION: We found previously unknown relationship between chemotaxis and electron transfer using LA system. The study has the potential of helping researchers to overcome the intrinsic metabolic limitation of the microorganisms for improving power density output of an MFC. BioMed Central 2010-05-21 /pmc/articles/PMC2886065/ /pubmed/20492688 http://dx.doi.org/10.1186/1471-2164-11-319 Text en Copyright © 2010 Tai et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Methodology Article Tai, Shang-Kai Wu, GuanI Yuan, Shinsheng Li, Ker-Chau Genome-wide expression links the electron transfer pathway of Shewanella oneidensis to chemotaxis |
title | Genome-wide expression links the electron transfer pathway of Shewanella oneidensis to chemotaxis |
title_full | Genome-wide expression links the electron transfer pathway of Shewanella oneidensis to chemotaxis |
title_fullStr | Genome-wide expression links the electron transfer pathway of Shewanella oneidensis to chemotaxis |
title_full_unstemmed | Genome-wide expression links the electron transfer pathway of Shewanella oneidensis to chemotaxis |
title_short | Genome-wide expression links the electron transfer pathway of Shewanella oneidensis to chemotaxis |
title_sort | genome-wide expression links the electron transfer pathway of shewanella oneidensis to chemotaxis |
topic | Methodology Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886065/ https://www.ncbi.nlm.nih.gov/pubmed/20492688 http://dx.doi.org/10.1186/1471-2164-11-319 |
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