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Matrix Metalloproteinase-Induced Epithelial-Mesenchymal Transition in Breast Cancer

Matrix metalloproteinases (MMPs) degrade and modify the extracellular matrix (ECM) as well as cell-ECM and cell-cell contacts, facilitating detachment of epithelial cells from the surrounding tissue. MMPs play key functions in embryonic development and mammary gland branching morphogenesis, but they...

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Detalles Bibliográficos
Autores principales: Radisky, Evette S., Radisky, Derek C.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886087/
https://www.ncbi.nlm.nih.gov/pubmed/20440544
http://dx.doi.org/10.1007/s10911-010-9177-x