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Profile of asymmetrical retinopathy of prematurity in twins

BACKGROUND: In twin births, both babies have the same gestational age and pre-natal conditions. However, twins may develop a varied retinopathy of prematurity (ROP) course depending on birth weight and other systemic factors. OBJECTIVE: To study the profile of asymmetric ROP in twins DESIGN: Retrosp...

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Detalles Bibliográficos
Autores principales: Azad, Rajvardhan, Chandra, Parijat, Patwardhan, Sourabh D, Gupta, Aparna
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886251/
https://www.ncbi.nlm.nih.gov/pubmed/20413923
http://dx.doi.org/10.4103/0301-4738.62645
Descripción
Sumario:BACKGROUND: In twin births, both babies have the same gestational age and pre-natal conditions. However, twins may develop a varied retinopathy of prematurity (ROP) course depending on birth weight and other systemic factors. OBJECTIVE: To study the profile of asymmetric ROP in twins DESIGN: Retrospective study SETTING: Tertiary ROP referral eye hospital. MATERIALS AND METHODS: The profile of 56 pairs of twins with ROP were studied and analyzed for differences in zone or need for treatment, while studying possible causes for the varied outcome. RESULTS: In 45 pairs of twins (80%) the disease progressed identically in both eyes, while in 11 pairs (20%) the ROP showed differences in zone or need for treatment. Four of these pairs were discordant. In 3 of these 4 pairs, the heavier birth weight twin had a more severe ROP course. CONCLUSIONS: Twins can present with asymmetric ROP course, and it is therefore essential to examine both twins as per screening protocols.