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Transmembrane TNF-α: structure, function and interaction with anti-TNF agents

Transmembrane TNF-α, a precursor of the soluble form of TNF-α, is expressed on activated macrophages and lymphocytes as well as other cell types. After processing by TNF-α-converting enzyme (TACE), the soluble form of TNF-α is cleaved from transmembrane TNF-α and mediates its biological activities t...

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Detalles Bibliográficos
Autores principales:	Horiuchi, Takahiko, Mitoma, Hiroki, Harashima, Shin-ichi, Tsukamoto, Hiroshi, Shimoda, Terufumi
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886310/ https://www.ncbi.nlm.nih.gov/pubmed/20194223 http://dx.doi.org/10.1093/rheumatology/keq031

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