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Role of kinase-independent and -dependent functions of FAK in endothelial cell survival and barrier function during embryonic development

Focal adhesion kinase (FAK) is essential for vascular development as endothelial cell (EC)–specific knockout of FAK (conditional FAK knockout [CFKO] mice) leads to embryonic lethality. In this study, we report the differential kinase-independent and -dependent functions of FAK in vascular developmen...

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Detalles Bibliográficos
Autores principales:	Zhao, Xiaofeng, Peng, Xu, Sun, Shaogang, Park, Ann Y.J., Guan, Jun-Lin
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886345/ https://www.ncbi.nlm.nih.gov/pubmed/20530207 http://dx.doi.org/10.1083/jcb.200912094

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