A robust cell cycle control mechanism limits E2F-induced proliferation of terminally differentiated cells in vivo

Terminally differentiated cells in Drosophila melanogaster wings and eyes are largely resistant to proliferation upon deregulation of either E2F or cyclin E (CycE), but exogenous expression of both factors together can bypass cell cycle exit. In this study, we show this is the result of cooperation...

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Detalles Bibliográficos
Autores principales: Buttitta, Laura A., Katzaroff, Alexia J., Edgar, Bruce A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886355/
https://www.ncbi.nlm.nih.gov/pubmed/20548101
http://dx.doi.org/10.1083/jcb.200910006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886355/
https://www.ncbi.nlm.nih.gov/pubmed/20548101
http://dx.doi.org/10.1083/jcb.200910006

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