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Direct Visualization of Protease Action on Collagen Triple Helical Structure
Enzymatic processing of extracellular matrix (ECM) macromolecules by matrix metalloproteases (MMPs) is crucial in mediating physiological and pathological cell processes. However, the molecular mechanisms leading to effective physiological enzyme-ECM interactions remain elusive. Only scant informati...
Autores principales: | Rosenblum, Gabriel, Van den Steen, Philippe E., Cohen, Sidney R., Bitler, Arkady, Brand, David D., Opdenakker, Ghislain, Sagi, Irit |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886829/ https://www.ncbi.nlm.nih.gov/pubmed/20585385 http://dx.doi.org/10.1371/journal.pone.0011043 |
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