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CD8+ T Cell Priming by Dendritic Cell Vaccines Requires Antigen Transfer to Endogenous Antigen Presenting Cells

BACKGROUND: Immunotherapeutic strategies to stimulate anti-tumor immunity are promising approaches for cancer treatment. A major barrier to their success is the immunosuppressive microenvironment of tumors, which inhibits the functions of endogenous dendritic cells (DCs) that are necessary for the g...

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Detalles Bibliográficos
Autores principales:	Yewdall, Alice W., Drutman, Scott B., Jinwala, Felecia, Bahjat, Keith S., Bhardwaj, Nina
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886840/ https://www.ncbi.nlm.nih.gov/pubmed/20585396 http://dx.doi.org/10.1371/journal.pone.0011144

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