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Bryostatin Modulates Latent HIV-1 Infection via PKC and AMPK Signaling but Inhibits Acute Infection in a Receptor Independent Manner

HIV's ability to establish long-lived latent infection is mainly due to transcriptional silencing in resting memory T lymphocytes and other non dividing cells including monocytes. Despite an undetectable viral load in patients treated with potent antiretrovirals, current therapy is unable to pu...

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Detalles Bibliográficos
Autores principales:	Mehla, Rajeev, Bivalkar-Mehla, Shalmali, Zhang, Ruonan, Handy, Indhira, Albrecht, Helmut, Giri, Shailendra, Nagarkatti, Prakash, Nagarkatti, Mitzi, Chauhan, Ashok
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886842/ https://www.ncbi.nlm.nih.gov/pubmed/20585398 http://dx.doi.org/10.1371/journal.pone.0011160

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