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Chloramphenicol Causes Mitochondrial Stress, Decreases ATP Biosynthesis, Induces Matrix Metalloproteinase-13 Expression, and Solid-Tumor Cell Invasion

Overuse and abuse of antibiotics can increase the risk of cancer. Chloramphenicol can inhibit both bacterial and mitochondrial protein synthesis, causing mitochondrial stress and decreased ATP biosynthesis. Chloramphenicol can accelerate cancer progression; however, the underlying mechanisms of chlo...

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Detalles Bibliográficos
Autores principales:	Li, Ching-Hao, Cheng, Yu-Wen, Liao, Po-Lin, Yang, Ya-Ting, Kang, Jaw-Jou
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Molecular Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886854/ https://www.ncbi.nlm.nih.gov/pubmed/20338993 http://dx.doi.org/10.1093/toxsci/kfq085

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