Renal hypoperfusion and impaired endothelium-dependent vasodilation in an animal model of VILI: the role of the peroxynitrite-PARP pathway

INTRODUCTION: Mechanical ventilation (MV) can injure the lungs and contribute to an overwhelming inflammatory response, leading to acute renal failure (ARF). We previously showed that poly(adenosine diphosphate-ribose) polymerase (PARP) is involved in the development of ventilator-induced lung injur...

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Detalles Bibliográficos
Autores principales: Vaschetto, Rosanna, Kuiper, Jan W, Musters, René JP, Eringa, Etto C, Della Corte, Francesco, Murthy, Kanneganti, Groeneveld, AB Johan, Plötz, Frans B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887157/
https://www.ncbi.nlm.nih.gov/pubmed/20346119
http://dx.doi.org/10.1186/cc8932

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