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BMP-2/6 Heterodimer Is More Effective than BMP-2 or BMP-6 Homodimers as Inductor of Differentiation of Human Embryonic Stem Cells

BACKGROUND: Bone Morphogenetic Protein (BMP) signaling pathways are involved in differentiation of stem cells into diverse cell types, and thus BMPs can be used as main guidance molecules for in vitro differentiation of human stem cells. METHODOLOGY/PRINCIPAL FINDINGS: We have analyzed the ability f...

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Detalles Bibliográficos
Autores principales: Valera, Elvira, Isaacs, Michael J., Kawakami, Yasuhiko, Izpisúa Belmonte, Juan Carlos, Choe, Senyon
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887366/
https://www.ncbi.nlm.nih.gov/pubmed/20567515
http://dx.doi.org/10.1371/journal.pone.0011167