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Benzo(a)pyrene induces similar gene expression changes in testis of DNA repair proficient and deficient mice
BACKGROUND: Benzo [a]pyrene (B[a]P) exposure induces DNA adducts at all stages of spermatogenesis and in testis, and removal of these lesions is less efficient in nucleotide excision repair deficient Xpc(-/- )mice than in wild type mice. In this study, we investigated by using microarray technology...
Autores principales: | Verhofstad, Nicole, Pennings, Jeroen LA, van Oostrom, Conny ThM, van Benthem, Jan, van Schooten, Frederik J, van Steeg, Harry, Godschalk, Roger WL |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887421/ https://www.ncbi.nlm.nih.gov/pubmed/20504355 http://dx.doi.org/10.1186/1471-2164-11-333 |
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