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Blockade of TRPM7 Channel Activity and Cell Death by Inhibitors of 5-Lipoxygenase
TRPM7 is a ubiquitous divalent-selective ion channel with its own kinase domain. Recent studies have shown that suppression of TRPM7 protein expression by RNA interference increases resistance to ischemia-induced neuronal cell death in vivo and in vitro, making the channel a potentially attractive p...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887440/ https://www.ncbi.nlm.nih.gov/pubmed/20567598 http://dx.doi.org/10.1371/journal.pone.0011161 |