Dynamic Switch of Negative Feedback Regulation in Drosophila Akt–TOR Signaling

Akt represents a nodal point between the Insulin receptor and TOR signaling, and its activation by phosphorylation controls cell proliferation, cell size, and metabolism. The activity of Akt must be carefully balanced, as increased Akt signaling is frequently associated with cancer and as insufficie...

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Detalles Bibliográficos
Autores principales: Kockel, Lutz, Kerr, Kimberly S., Melnick, Michael, Brückner, Katja, Hebrok, Matthias, Perrimon, Norbert
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887466/
https://www.ncbi.nlm.nih.gov/pubmed/20585550
http://dx.doi.org/10.1371/journal.pgen.1000990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887466/
https://www.ncbi.nlm.nih.gov/pubmed/20585550
http://dx.doi.org/10.1371/journal.pgen.1000990

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