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Dynamic Switch of Negative Feedback Regulation in Drosophila Akt–TOR Signaling
Akt represents a nodal point between the Insulin receptor and TOR signaling, and its activation by phosphorylation controls cell proliferation, cell size, and metabolism. The activity of Akt must be carefully balanced, as increased Akt signaling is frequently associated with cancer and as insufficie...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887466/ https://www.ncbi.nlm.nih.gov/pubmed/20585550 http://dx.doi.org/10.1371/journal.pgen.1000990 |