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NONDERMATOPHYTIC MOULDS AS A CAUSATIVE AGENT OF ONYCHOMYCOSIS IN TEHRAN
BACKGROUND: In the last few years the number of cases of nondermatophytic onychomycosis has greatly increased. AIM: To evaluate the incidence, the clinic characteristics, and predisposing factors of nondermatophytic onychomycosis. MATERIALS AND METHODS: All collected specimens were analyzed by direc...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887516/ https://www.ncbi.nlm.nih.gov/pubmed/20606881 http://dx.doi.org/10.4103/0019-5154.62743 |
Sumario: | BACKGROUND: In the last few years the number of cases of nondermatophytic onychomycosis has greatly increased. AIM: To evaluate the incidence, the clinic characteristics, and predisposing factors of nondermatophytic onychomycosis. MATERIALS AND METHODS: All collected specimens were analyzed by direct microscopy and culture. Microscopic examination of these specimens was carried out in potassium hydroxide solution (20%) with dimethyl sulfoxide (4%). These specimens were cultured on sabouraud's glucose agar with chloramphenicol and sabouraud's glucose agar with chloramphenicol and cycloheximide. Cultures were incubated at 25°C for up to 28 days and checked twice weekly for growth. RESULTS: Nondermatophytic onychomycosis were 11.5% of all onychomycosis. We found that Aspergillus spp. were the more responsible etiologic agents of nondermatophytic onychomycosis, resulting in a total of 28 patients (59.6%). In our study other causative agents were Acremonium spp. (17%), Fusarium spp. (12.7%), Geotrichum spp. (4.2%), Trichosporun spp., (4.2%) and Scopulariopsis spp (2.1%). In our patients moulds onychomycosis developed mainly in toenails (74.5%). CONCLUSION: Knowing the exact pathogen is important and has implications in therapy and prognosis. |
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