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NONDERMATOPHYTIC MOULDS AS A CAUSATIVE AGENT OF ONYCHOMYCOSIS IN TEHRAN

BACKGROUND: In the last few years the number of cases of nondermatophytic onychomycosis has greatly increased. AIM: To evaluate the incidence, the clinic characteristics, and predisposing factors of nondermatophytic onychomycosis. MATERIALS AND METHODS: All collected specimens were analyzed by direc...

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Autores principales: Bassiri-Jahromi, Shahindokht, Khaksar, Ali Asgar
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887516/
https://www.ncbi.nlm.nih.gov/pubmed/20606881
http://dx.doi.org/10.4103/0019-5154.62743
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author Bassiri-Jahromi, Shahindokht
Khaksar, Ali Asgar
author_facet Bassiri-Jahromi, Shahindokht
Khaksar, Ali Asgar
author_sort Bassiri-Jahromi, Shahindokht
collection PubMed
description BACKGROUND: In the last few years the number of cases of nondermatophytic onychomycosis has greatly increased. AIM: To evaluate the incidence, the clinic characteristics, and predisposing factors of nondermatophytic onychomycosis. MATERIALS AND METHODS: All collected specimens were analyzed by direct microscopy and culture. Microscopic examination of these specimens was carried out in potassium hydroxide solution (20%) with dimethyl sulfoxide (4%). These specimens were cultured on sabouraud's glucose agar with chloramphenicol and sabouraud's glucose agar with chloramphenicol and cycloheximide. Cultures were incubated at 25°C for up to 28 days and checked twice weekly for growth. RESULTS: Nondermatophytic onychomycosis were 11.5% of all onychomycosis. We found that Aspergillus spp. were the more responsible etiologic agents of nondermatophytic onychomycosis, resulting in a total of 28 patients (59.6%). In our study other causative agents were Acremonium spp. (17%), Fusarium spp. (12.7%), Geotrichum spp. (4.2%), Trichosporun spp., (4.2%) and Scopulariopsis spp (2.1%). In our patients moulds onychomycosis developed mainly in toenails (74.5%). CONCLUSION: Knowing the exact pathogen is important and has implications in therapy and prognosis.
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spelling pubmed-28875162010-07-02 NONDERMATOPHYTIC MOULDS AS A CAUSATIVE AGENT OF ONYCHOMYCOSIS IN TEHRAN Bassiri-Jahromi, Shahindokht Khaksar, Ali Asgar Indian J Dermatol Original Article BACKGROUND: In the last few years the number of cases of nondermatophytic onychomycosis has greatly increased. AIM: To evaluate the incidence, the clinic characteristics, and predisposing factors of nondermatophytic onychomycosis. MATERIALS AND METHODS: All collected specimens were analyzed by direct microscopy and culture. Microscopic examination of these specimens was carried out in potassium hydroxide solution (20%) with dimethyl sulfoxide (4%). These specimens were cultured on sabouraud's glucose agar with chloramphenicol and sabouraud's glucose agar with chloramphenicol and cycloheximide. Cultures were incubated at 25°C for up to 28 days and checked twice weekly for growth. RESULTS: Nondermatophytic onychomycosis were 11.5% of all onychomycosis. We found that Aspergillus spp. were the more responsible etiologic agents of nondermatophytic onychomycosis, resulting in a total of 28 patients (59.6%). In our study other causative agents were Acremonium spp. (17%), Fusarium spp. (12.7%), Geotrichum spp. (4.2%), Trichosporun spp., (4.2%) and Scopulariopsis spp (2.1%). In our patients moulds onychomycosis developed mainly in toenails (74.5%). CONCLUSION: Knowing the exact pathogen is important and has implications in therapy and prognosis. Medknow Publications 2010 /pmc/articles/PMC2887516/ /pubmed/20606881 http://dx.doi.org/10.4103/0019-5154.62743 Text en © Indian Journal of Dermatology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Bassiri-Jahromi, Shahindokht
Khaksar, Ali Asgar
NONDERMATOPHYTIC MOULDS AS A CAUSATIVE AGENT OF ONYCHOMYCOSIS IN TEHRAN
title NONDERMATOPHYTIC MOULDS AS A CAUSATIVE AGENT OF ONYCHOMYCOSIS IN TEHRAN
title_full NONDERMATOPHYTIC MOULDS AS A CAUSATIVE AGENT OF ONYCHOMYCOSIS IN TEHRAN
title_fullStr NONDERMATOPHYTIC MOULDS AS A CAUSATIVE AGENT OF ONYCHOMYCOSIS IN TEHRAN
title_full_unstemmed NONDERMATOPHYTIC MOULDS AS A CAUSATIVE AGENT OF ONYCHOMYCOSIS IN TEHRAN
title_short NONDERMATOPHYTIC MOULDS AS A CAUSATIVE AGENT OF ONYCHOMYCOSIS IN TEHRAN
title_sort nondermatophytic moulds as a causative agent of onychomycosis in tehran
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887516/
https://www.ncbi.nlm.nih.gov/pubmed/20606881
http://dx.doi.org/10.4103/0019-5154.62743
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