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Overexpression of CDC25B, CDC25C and phospho-CDC25C (Ser216) in vulvar squamous cell carcinomas are associated with malignant features and aggressive cancer phenotypes
BACKGROUND: CDC25 phosphatases are important regulators of the cell cycle. Their abnormal expression detected in a number of tumors implies that their dysregulation is involved in malignant transformation. However, the role of CDC25s in vulvar cancer is still unknown. To shed light on their roles in...
Autores principales: | Wang, Zhihui, Trope, Claes G, Flørenes, Vivi Ann, Suo, Zhenhe, Nesland, Jahn M, Holm, Ruth |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887779/ https://www.ncbi.nlm.nih.gov/pubmed/20500813 http://dx.doi.org/10.1186/1471-2407-10-233 |
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