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The val(158)met polymorphism of human catechol-O-methyltransferase (COMT) affects anterior cingulate cortex activation in response to painful laser stimulation

BACKGROUND: Pain is a complex experience with sensory, emotional and cognitive aspects. Genetic and environmental factors contribute to pain-related phenotypes such as chronic pain states. Genetic variations in the gene coding for catechol-O-methyltransferase (COMT) have been suggested to affect cli...

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Detalles Bibliográficos
Autores principales: Mobascher, Arian, Brinkmeyer, Juergen, Thiele, Holger, Toliat, Mohammad R, Steffens, Michael, Warbrick, Tracy, Musso, Francesco, Wittsack, Hans-Joerg, Saleh, Andreas, Schnitzler, Alfons, Winterer, Georg
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887789/
https://www.ncbi.nlm.nih.gov/pubmed/20509977
http://dx.doi.org/10.1186/1744-8069-6-32

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