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The val(158)met polymorphism of human catechol-O-methyltransferase (COMT) affects anterior cingulate cortex activation in response to painful laser stimulation
BACKGROUND: Pain is a complex experience with sensory, emotional and cognitive aspects. Genetic and environmental factors contribute to pain-related phenotypes such as chronic pain states. Genetic variations in the gene coding for catechol-O-methyltransferase (COMT) have been suggested to affect cli...
Autores principales: | Mobascher, Arian, Brinkmeyer, Juergen, Thiele, Holger, Toliat, Mohammad R, Steffens, Michael, Warbrick, Tracy, Musso, Francesco, Wittsack, Hans-Joerg, Saleh, Andreas, Schnitzler, Alfons, Winterer, Georg |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887789/ https://www.ncbi.nlm.nih.gov/pubmed/20509977 http://dx.doi.org/10.1186/1744-8069-6-32 |
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