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A highly attenuated recombinant human respiratory syncytial virus lacking the G protein induces long-lasting protection in cotton rats
BACKGROUND: Respiratory syncytial virus (RSV) is a primary cause of serious lower respiratory tract illness for which there is still no safe and effective vaccine available. Using reverse genetics, recombinant (r)RSV and an rRSV lacking the G gene (ΔG) were constructed based on a clinical RSV isolat...
Autores principales: | Widjojoatmodjo, Myra N, Boes, Jolande, van Bers, Marleen, van Remmerden, Yvonne, Roholl, Paul JM, Luytjes, Willem |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887800/ https://www.ncbi.nlm.nih.gov/pubmed/20525213 http://dx.doi.org/10.1186/1743-422X-7-114 |
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