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A combined HM-PCR/SNuPE method for high sensitive detection of rare DNA methylation
BACKGROUND: DNA methylation changes are widely used as early molecular markers in cancer detection. Sensitive detection and classification of rare methylation changes in DNA extracted from circulating body fluids or complex tissue samples is crucial for the understanding of tumor etiology, clinical...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887863/ https://www.ncbi.nlm.nih.gov/pubmed/20525169 http://dx.doi.org/10.1186/1756-8935-3-12 |