Cargando…

Biotransformation of ginsenosides Rb(1), Rg(3 )and Rh(2 )in rat gastrointestinal tracts

BACKGROUND: Ginsenosides such as Rb(1), Rg(3 )and Rh(2 )are major bioactive components of Panax ginseng. This in vivo study investigates the metabolic pathways of ginsenosides Rb(1), Rg(3 )and Rh(2 )orally administered to rats. METHODS: High performance liquid chromatography-mass spectrometry (LC-MS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qian, Tianxiu, Cai, Zongwei
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887866/ https://www.ncbi.nlm.nih.gov/pubmed/20504301 http://dx.doi.org/10.1186/1749-8546-5-19

Ejemplares similares

Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions
por: Mohanan, Padmanaban, et al.
Publicado: (2018)

Comparative Pharmacokinetics of Ginsenoside Rg(3) and Ginsenoside Rh(2) after Oral Administration of Ginsenoside Rg(3) in Normal and Walker 256 Tumor-bearing Rats
por: Fan, He, et al.
Publicado: (2016)

Kinetic study for the optimization of ginsenoside Rg3 production by heat treatment of ginsenoside Rb1
por: Vo, Hoang Tung, et al.
Publicado: (2015)

Biotransformation of Ginsenoside Rf to Rh(1) by Recombinant β-Glucosidase
por: Ruan, Chang-Chun, et al.
Publicado: (2009)

Ginsenoside Rg3 induces ginsenoside Rb1-comparable cardioprotective effects independent of reducing blood pressure in spontaneously hypertensive rats
por: Jiang, Yichuan, et al.
Publicado: (2017)

Biotransformation of ginsenoside Rb1 via the gypenoside pathway by human gut bacteria
por: Shen, Hong, et al.
Publicado: (2013)

Neuroprotective effects of ginsenosides Rh(1 )and Rg(2 )on neuronal cells
por: Li, Xiao-Fan, et al.
Publicado: (2011)

Evaluation of glucosidases of Aspergillus niger strain comparing with other glucosidases in transformation of ginsenoside Rb1 to ginsenosides Rg3
por: Chang, Kyung Hoon, et al.
Publicado: (2013)

Metabolism Study of Notoginsenoside R(1), Ginsenoside Rg(1) and Ginsenoside Rb(1) of Radix Panax Notoginseng in Zebrafish
por: Wei, Yingjie, et al.
Publicado: (2011)

Protective effects of ginsenosides Rg1 and Rb1 against cognitive impairment induced by simulated microgravity in rats
por: Jiang, Ning, et al.
Publicado: (2023)

Biotransformation of Ginsenoside Rb(1) to Prosapogenins, Gypenoside XVII, Ginsenoside Rd, Ginsenoside F(2), and Compound K by Leuconostoc mesenteroides DC102
por: Quan, Lin-Hu, et al.
Publicado: (2011)

Metabolic Activities of Ginseng and Its Constituents, Ginsenoside Rb(1) and Rg(1), by Human Intestinal Microflora
por: Choi, Jong-Ryul, et al.
Publicado: (2011)

Enzymatic Biotransformation of Ginsenoside Rb1 and Gypenoside XVII into Ginsenosides Rd and F2 by Recombinant β-glucosidase from Flavobacterium johnsoniae
por: Hong, Hao, et al.
Publicado: (2012)

Highly Efficient Biotransformation of Notoginsenoside R1 into Ginsenoside Rg1 by Dictyoglomus thermophilum β-xylosidase Xln-DT
por: Li, Qi, et al.
Publicado: (2022)

Ginsenosides Rb1 and Rg1 Stimulate Melanogenesis in Human Epidermal Melanocytes via PKA/CREB/MITF Signaling
por: Lin, Mao, et al.
Publicado: (2014)

Pharmacokinetics of Ginsenoside Rb1, Rg3, Rk1, Rg5, F2, and Compound K from Red Ginseng Extract in Healthy Korean Volunteers
por: Kim, Hyung Joong, et al.
Publicado: (2022)

Morphine dependence is attenuated by red ginseng extract and ginsenosides Rh2, Rg3, and compound K
por: Yayeh, Taddesse, et al.
Publicado: (2016)

Enzymatic Biotransformation of Ginsenoside Rb(2) into Rd by Recombinant α-L-Arabinopyranosidase from Blastococcus saxobsidens
por: Kim, Ju-Hyeon, et al.
Publicado: (2020)

Biotransformation of Major Ginsenoside Rb(1) to Rd by Dekkera anomala YAE-1 from Mongolian Fermented Milk (Airag)
por: Renchinkhand, Gereltuya, et al.
Publicado: (2020)

Microbial transformation of ginsenoside Rb1, Re and Rg1 and its contribution to the improved anti-inflammatory activity of ginseng
por: Yu, Shanshan, et al.
Publicado: (2017)

Antiobesity and Antihyperglycemic Effects of Ginsenoside Rb1 in Rats
por: Xiong, Ye, et al.
Publicado: (2010)

Anti-Angiogenic Properties of Ginsenoside Rg3
por: Nakhjavani, Maryam, et al.
Publicado: (2020)

Detection of 13 Ginsenosides (Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, Rg3, Rh2, F1, Compound K, 20(S)-Protopanaxadiol, and 20(S)-Protopanaxatriol) in Human Plasma and Application of the Analytical Method to Human Pharmacokinetic Studies Following Two Week-Repeated Administration of Red Ginseng Extract
por: Jin, Sojeong, et al.
Publicado: (2019)

Characterizing a Full Spectrum of Physico-Chemical Properties of Ginsenosides Rb(1) and Rg(1) to Be Proposed as Standard Reference Materials
por: Kim, Il-Woung, et al.
Publicado: (2011)

Preparation of Ginseng Extract with Enhanced Levels of Ginsenosides Rg1 and Rb1 Using High Hydrostatic Pressure and Polysaccharide Hydrolases
por: Palaniyandi, Sasikumar Arunachalam, et al.
Publicado: (2017)

Ginsenoside Rg3 inhibits the biological activity of SGC‐7901
por: Yang, Qing, et al.
Publicado: (2020)

Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg1
por: Hsieh, Chao-Chieh, et al.
Publicado: (2023)

Ginsenoside Rg2 Attenuated Trastuzumab-Induced Cardiotoxicity in Rats
por: Liu, Guang, et al.
Publicado: (2022)

The anxiolytic-like effects of ginsenoside Rg3 on chronic unpredictable stress in rats
por: Xu, Jia-ning, et al.
Publicado: (2018)

Evaluation of the adaptogenic potential exerted by ginsenosides Rb1 and Rg1 against oxidative stress-mediated neurotoxicity in an in vitro neuronal model
por: Fernández-Moriano, Carlos, et al.
Publicado: (2017)

Ginsenoside Rg1 and 20(S)-Rg3 Induce IgA Production by Mouse B Cells
por: Park, Ha-Yan, et al.
Publicado: (2015)

Pharmacokinetic Comparison of 20(R)- and 20(S)-Ginsenoside Rh1 and 20(R)- and 20(S)-Ginsenoside Rg3 in Rat Plasma following Oral Administration of Radix Ginseng Rubra and Sheng-Mai-San Extracts
por: Fan, Xiaomei, et al.
Publicado: (2017)

Biotransformation of major ginsenosides in ginsenoside model culture by lactic acid bacteria
por: Park, Seong-Eun, et al.
Publicado: (2017)

Relationship Between Ginsenoside Rg3 and Metabolic Syndrome
por: Lee, Hyunji, et al.
Publicado: (2020)

Prebiotics enhance the biotransformation and bioavailability of ginsenosides in rats by modulating gut microbiota
por: Zhang, Xiaoyan, et al.
Publicado: (2021)

Comparison of the Protective Effects of Ginsenosides Rb1 and Rg1 on Improving Cognitive Deficits in SAMP8 Mice Based on Anti-Neuroinflammation Mechanism
por: Yang, Yujie, et al.
Publicado: (2020)

Effects of Ginsenoside Rb(1) on Skin Changes
por: Kimura, Yoshiyuki, et al.
Publicado: (2012)

Inhibition of in vitro Tumor Cell Invasion by Ginsenoside Rg(3)
por: Shinkai, Kiyoko, et al.
Publicado: (1996)

Polymer-Based Wound Dressings Loaded with Ginsenoside Rg3
por: Yang, Jiali, et al.
Publicado: (2023)

Pharmacological activities of ginsenoside Rg5 (Review)
por: Liu, Ming-Yang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_e3p10bo8ep40q4mabnb4rgfab9