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Targeting of the cytosolic poly(A) binding protein PABPC1 to mitochondria causes mitochondrial translation inhibition

Mammalian mitochondria contain their own genome that is almost fully transcribed from both strands, generating polycistronic RNA units that are processed and matured. The mitochondrial mRNA is modified by oligo- or polyadenylation at the 3′ termini, but the exact function of this post-transcriptiona...

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Detalles Bibliográficos
Autores principales: Wydro, Mateusz, Bobrowicz, Agnieszka, Temperley, Richard J., Lightowlers, Robert N., Chrzanowska-Lightowlers, Zofia M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887948/
https://www.ncbi.nlm.nih.gov/pubmed/20144953
http://dx.doi.org/10.1093/nar/gkq068