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Targeting of the cytosolic poly(A) binding protein PABPC1 to mitochondria causes mitochondrial translation inhibition
Mammalian mitochondria contain their own genome that is almost fully transcribed from both strands, generating polycistronic RNA units that are processed and matured. The mitochondrial mRNA is modified by oligo- or polyadenylation at the 3′ termini, but the exact function of this post-transcriptiona...
Autores principales: | Wydro, Mateusz, Bobrowicz, Agnieszka, Temperley, Richard J., Lightowlers, Robert N., Chrzanowska-Lightowlers, Zofia M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887948/ https://www.ncbi.nlm.nih.gov/pubmed/20144953 http://dx.doi.org/10.1093/nar/gkq068 |
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