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State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation
The voltage-sensing domain of voltage-gated channels is comprised of four transmembrane helices (S1–S4), with conserved positively charged residues in S4 moving across the membrane in response to changes in transmembrane voltage. Although it has been shown that positive charges in S4 interact with n...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888051/ https://www.ncbi.nlm.nih.gov/pubmed/20479111 http://dx.doi.org/10.1085/jgp.201010408 |