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Identification of a protein–protein interaction between KCNE1 and the activation gate machinery of KCNQ1
KCNQ1 channels assemble with KCNE1 transmembrane (TM) peptides to form voltage-gated K(+) channel complexes with slow activation gate opening. The cytoplasmic C-terminal domain that abuts the KCNE1 TM segment has been implicated in regulating KCNQ1 gating, yet its interaction with KCNQ1 has not been...
Autores principales: | Lvov, Anatoli, Gage, Steven D., Berrios, Virla M., Kobertz, William R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888057/ https://www.ncbi.nlm.nih.gov/pubmed/20479109 http://dx.doi.org/10.1085/jgp.200910386 |
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